Schouten T, Prinsze K, Henry A, Daamen L, Besselink M, Bonsing B et al.
Lancet Gastrenterol Hepatol 2026; 11: 323-333.
Some 1090 patients were included with median follow-up of 56 months, and algorithm-based care was associated with improved overall survival (adjusted hazard ratio 0.76, 95 per cent confidence interval 0.62 to 0.93, P=0.0089). Overall survival difference between groups was most pronounced in the subset of patients with pancreatic ductal adenocarcinoma (adjusted hazard ratio 0.71, 0.56 to 0.90, P=0.0052).
Comment: Intriguing post-hoc finding from the PORSCH trial: early algorithm-based complication management after pancreatic resection is associated with improved long-term survival.
